This book represents the preface to the nine-hundred theses on the meaning of man in the world from the perspective of a 15th century prince, mystic, philosopher, alchemist. In this salubrious text we see Pico della Mirandola attempting to fuse the varied religious and philosophical traditions of Zoroaster, ancient Judaism, Plato, and Aristotle into a laudation of the creation of man by the Divine. This text is the founding statement of the "humanist" doctorine which argues that God gave Man "free will" which (if used virtuously) allows man to strive for dignity in the eyes of a beneficent God. This translation aptly conveys the passion and erudition of this great philosopher.

The Oration on the Dignity of Man (De hominis dignitate) is a famous public discourse pronounced in 1486 by Pico della Mirandola, an Italian scholar and philosopher of the Renaissance. It has been called the "Manifesto of the Renaissance".

Pico, who belonged to the family that had long dwelt in the Castle of Mirandola, left his share of the ancestral principality to his two brothers to devote himself wholly to study. In his fourteenth year, he went to Bologna to study canon law and fit himself for the ecclesiastical career. Repelled by the purely positive science of law,[citation needed] he devoted himself to the study of philosophy and theology, and spent seven years wandering through the chief universities of Italy and France, studying Greek, Latin, Hebrew, Syriac, and Arabic.

Count Giovanni Pico della Mirandola (24 February 1463 – 17 November 1494) was an Italian Renaissance philosopher. He is famed for the events of 1486, when at the age of 23, he proposed to defend 900 theses on religion, philosophy, natural philosophy, and magic against all comers, for which he wrote the famous Oration on the Dignity of Man, which has been called the "Manifesto of the Renaissance", and a key text of Renaissance humanism and of what has been called the "Hermetic Reformation".